6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Names and Identifiers

Name	Pymetrozine
Synonyms	A 9364A Hsdb 7054 Pymetrozin Pymetrozine Pymetrozine 0 Pymetrozin Solution, 100ppm (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one 6-Methyl-4-((pyridin-3-ylMethylene)aMino)-4,5-dihydro-1,2,4-triazin-3(2H)-one E)-4,5-dihydro-6-methyl-4-[(3-pyridinylmethylene)amino]-1,2,4-triazin-3(2H)-one (E)-4,5-dihydro-6-Methyl-4-[(3-pyridinylMethylene)aMino]-1,2,4-triazin-3(2H)-one 4,5-Dihydro-6-Methyl-4-[(E)-(3-pyridinylMethylene)aMino]-1,2,4-triazin-3(2H)-one (E)-4,5-Fihydro-6-methyl-4-((3-pyridinylmethylene)amino)-1,2,4-triazin-3(2H)-one (E)-6-Methyl-4-((pyridin-3-ylMethylene)aMino)-4,5-dihydro-1,2,4-triazin-3(2H)-one 6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one
CAS	123312-89-0
EINECS	200-258-5
InChI	InChI=1/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+
InChIKey	QHMTXANCGGJZRX-WUXMJOGZSA-N

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Physico-chemical Properties

Molecular Formula	C10H11N5O
Molar Mass	217.23
Density	1.36g/cm3 (20～25℃）
Melting Point	234.4°
Flash Point	>230°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0Pa at 25.03℃
Appearance	Colorless crystal
Color	White to Light Beige
BRN	7814151
pKa	12.90±0.40(Predicted)
Storage Condition	0-6°C
Stability	Hygroscopic
Refractive Index	1.665
MDL	MFCD01632346
In vivo study	Pymetrozine, a fast-acting and selective inhibitor of aphid feeding. In-situ studies with electronic monitoring of feeding behaviour. Pymetrozine, a pyridine azomethine compound, represents a novel insecticide with a selective activity against homopteran insects. It acts in a unique way: aphids are not knocked down on contact but seem to die of starvation. This implies an effect of Pymetrozine on feeding behaviour. The aim of the present work is to elucidate how and at which step Pymetrozine interferes with the complex mechanisms underlying phloem feeding. The effect of Pymetrozine, applied in various ways, on different phases of stylet penetration and feeding activity of individual aphids is studied using the Electrical Penetration Graph technique (EPG). Initial choice experiments indicated that Pymetrozine does not have a deterrent or antifeedant action. Topical application (150 ng/mg fresh weight) inhibits stylet insertion into the plant. When injected, less than 30 ng/mg is sufficient to produce the same effect. When Pymetrozine is systemically applied via plant spraying or root uptake, aphids started feeding normally. After some time, however, they withdrew their stylets from the phloem and walked around with unaffected locomotion. At low doses aphids eventually recovered and resumed feeding. High doses, however, irreversibly disrupted feeding and prevented stylet reinsertion. Aphid motility is not affected up to an estimated haemolymph concentration of 1 mM Pymetrozine. Aphids which eventually stopped feeding on Pymetrozine-treated plants showed EPGs with distorted salivation/ingestion patterns.

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R40 - Limited evidence of a carcinogenic effect R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany	2
RTECS	XZ3018620
HS Code	29336990
Toxicity	LD50 orally in rats: 5820 mg/kg (Flückiger)

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Reference Information

LogP	-0.18 at 25℃ and pH7.1
surface tension	69.4-72.3mN/m at 10g/L and 20 ℃
dissociation constant	0.19-4.07 at 20 ℃
EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
Overview	Pymetrozine pymetrozine was developed by the former Novartis Company of Switzerland in 1988. Pymetrozine is a pyridine or triazinone insecticide.
use	pymetrozine has high control effect on aphids, planthoppers, leafhoppers, whiteflies, etc. of crops such as rice, vegetables, cotton, wheat and fruit trees. The agent has excellent selectivity to homoptera pests, and its selectivity to aphids is better than the best anti-aphid agent-anti-aphid, and it also has good absorption.
Biological activity	Pymetrozine is a feeding inhibitor of the same wing, which can prevent the aphid species Mysus persicae (Sulzer) from spreading the cauliflower potato Mucor virus.
target	Homoptera
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)

Last Update：2024-04-10 22:29:15

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one

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Guangzhou Yuanda New Material Co.,Ltd

Product Name: Pymetrozine Request for quotation
CAS: 123312-89-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589

Wechat: +86 19849939632

Shanghai Yuanye Bio-Technology Co., Ltd.

Multiple Specifications

Product Name: Pymetrozine Visit Supplier Webpage Request for quotation
CAS: 123312-89-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one

Pymetrozine

CAS: 123312-89-0

Molecular Formula: C10H11N5O

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Names and Identifiers

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Physico-chemical Properties

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Risk and Safety

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Reference Information

Supplier List

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one Request for Quotation

Pymetrozine

CAS: 123312-89-0

Molecular Formula: C10H11N5O

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Names and Identifiers

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Physico-chemical Properties

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Risk and Safety

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one - Reference Information

Supplier List

6-methyl-4-{[(E)-pyridin-3-ylmethylidene]amino}-4,5-dihydro-1,2,4-triazin-3(2H)-one